References

ACPD

Atmospheric Chemistry and Physics Discussions

ACPD

1680-7375

Copernicus GmbH

Göttingen, Germany

10.5194/acpd-8-1-2008

Estimated UV doses to psoriasis patients during climate therapy at Gran Canaria in March 2006

Nilsen

L. T. N.

¹ Søyland

² Krogstad

A. L.

² ³

Norwegian Radiation Protection Authority, Østerås, Norway

Section for Climatotherapy, Department of Reumatology, Rikshospitalet University Hospital, Oslo, Norway

Department of Dermatology, Rikshospitalet University Hospital, Oslo, Norway

02 01 2008

8 1 1 19

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Psoriasis is a chronic inflammatory disease involving about 2–3% of the Norwegian population. Sun exposure has a positive effect on most psoriasis lesions, but ultraviolet (UV) radiation also causes a direct DNA damage in the skin cells and comprises a carcinogenic potential. UV exposure on the skin causes a local as well as a systemic immune suppressive effect, but the relation between sun exposure and these biological effects is not well known. In March 2006 a study was carried out to investigate possible therapeutic outcome mechanisms in 20 psoriasis patients receiving climate therapy at Gran Canaria. This paper presents estimates of their individual skin UV-doses based on UV measurements and the patients' diaries with information on time spent in the sun. <br></br> On the first day of exposure the patients received on average 5.1 Standard Erythema Doses (SED: median=4.0 SED, range 2.6–10.3 SED) estimated to the skin. During the 15 days study they received 165.8 SED (range 104.3–210.1 SED). The reduction in PASI score was 72.8% on average, but there was no obvious relation between the improvement and the UV dose. The UV doses were higher than those found from climate therapy studies at other locations. It seems beneficial to use more strict exposure schedules that consider the available UV irradiance, depending on time of the day, time of the year and weather conditions.

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