We present first observationally based validations of the space-borne lidar CALIOP onboard CALIPSO satellite using coincidental observations from a ground-based SNU lidar for 3 different types of atmospheric scenes. Both lidar measurements were taken in nearly same airmass in space and time. Total attenuated backscatters at 532 nm from the two instruments show similar aerosol and cloud layer structures (the top and bottom heights) both under cloud-free conditions and in case of multi-aerosol layers underlying semi-transparent cirrus clouds. This result confirms that the CALIPSO science team algorithms of the discrimination of cloud and aerosol as well as of their layer top and base altitudes are sound. Under thick clouds conditions, only information on the cloud top (bottom) height is reliable from CALIOP (ground-based lidar) observations due to strong signal attenuations. However, simultaneous space-borne CALIOP and ground-based SNU lidar measurements complement each other and provide full information on the vertical distribution of aerosols and clouds. Discrepancies between space-borne and ground-based lidar signals are partly explained by the strong spatial and vertical inhomogeneous distributions of clouds at few kilometer horizontal scales.